Approach to: Venous Thromboembolism

Venous thromboembolisms can manifest as a spectrum of diseases and complications, such deep vein thrombosis (DVT) pulmonary embolism (PE), consequence hypercoagulability, endothelial damage and/or venous stasis. DVT present localized pain or heaviness, unilateral edema, dilatation superficial nonvaricose veins, palpable cord Homans’s sign. Symptoms PE include acute worsening shortness breath pleuritic chest while physical examination may be remarkable for tachycardia tachypnea. However, given their non-specificity, using these signs symptoms alone allows poor differentiation between VTE other entities. This review will focus on multi-step diagnostic tree allowing evidence-based interpretation tests following determined pre-test probability (PTP), per Thrombosis Canada recommendations ASH clinical guidelines. An introduction to in Pediatrics pregnancy also discussed.